罗汉果甜甙对小鼠细胞免疫功能的调节作用

Regulation on the Immunological Effect of M ogrosides in the Mice

目的:观察罗汉果甜甙对小鼠细胞免疫功能的调节作用。方法:用罗汉果甜甙给正常和环磷酰胺(CTX)抑制小鼠灌胃,检测小鼠巨噬细胞吞噬功能和T细胞的增殖作用。结果:显示罗汉果甜甙对正常小鼠免疫功能无明显作用,但能显著提高CTX免疫抑制小鼠的巨噬细胞吞噬功能和T细胞的增殖作用。结论:罗汉果甜甙对CTX免疫抑制小鼠的细胞免疫功能具有一定的正调节作用。

Objective:To investigate the cellular immunological effect of mogrosides in the mice. Methods:Mogrosides was administered to normal or CTX-induced immunosuppressive mice, and their macrophage function and T lymphocyte proliferation were detected.Results:Mogrosides could promote phagocytosis and T lymphocyte proliferation significantly in the CTX-induced immunosuppressive mice, but not in the normal mice.Conclusion:The results suggested that mogrosides had certain up-regulation on cellular immunity in the CT...