天南星(虎掌南星)抗惊厥作用探讨

Study on Anticonvulsive Effect of Rhizoma Pinelliae

以对抗士的宁引起小鼠强直性惊厥及死亡为指标,比较研究了天南星不同温度提取的水溶物的抗惊厥作用。结果发现天南星冷浸出物对士的宁引起小鼠惊厥有明显抑制作用,且可明显降低惊厥小鼠的死亡率。提示天南星水溶性成分有一定抗惊厥作用,且这类成分加热可被破坏。

Anticonvulsive effect of water-soluble extract of Rhizoma Pinelliae was studied. The result showed that the extract of Rhizoma Pinelliae could remarkably inhibit the convulsion induced by strychnine and obviously reduce mortality rate in mice. But the extract could be destroyed easily by heat.