中药复方“体复康”对剧烈运动后大鼠巨噬细胞功能恢复的影响

Effects of "Tifukang" on Immune Function in Rats after Intense Exercise

为了解新型抗运动性疲劳中药“体复康”对剧烈运动后机体免疫功能的作用效果，以雄性SD大鼠为实验动物，在长期大强度训练的同时服用该中药，建立运动疲劳模型，采用腹腔巨噬细胞TNF（肿瘤坏死因子）、IL－1（白细胞介素1）、IL－6（白细胞介素6）分泌功能指标进行研究，主要结果如下：中药对巨噬细胞分泌TNF的显著作用（p＜0．001）。中药与运动后恢复时间的交互作用十分显著：服用中药显著提高了大鼠安静状态下腹腔巨噬细胞分泌TNF的功能，并使TNF分泌功能基本不受力竭运动的影响，剧烈运动后所观察的3小时之内TNF分泌功能未下降，而对照组分泌TNF功能迅速下降。中药对大鼠腹腔巨噬细胞IL－1产生能力没有产生明显作用（P＞0．05）。中药对巨噬细胞分泌IL－6的功能有显著的作用（P＜0．05），服用中药的大鼠在力竭运动后3／小时巨噬细胞分泌IL－6的功能显著高于对照组（p＜0．05）。推论理气扶正类中药可能有维持或促进剧烈运动后免疫功能恢复的作用。

Male SD rats were trained with high intensity for 7 weeks, and in the meanwhile a new type of Chinese herbs compoundwhich can regulate "qi- flow" and strengthening the "vital - qi" were drinistered through intragastic perfusion. These ratswere used to establish an exhausted model to approach the effect of the herbs on the immune function. The ability to ProduceTNF, IL-1, IL- 6 was detendned, and the results was as follows: the Chinese herha and the interachons between the heraland the recovery time have s...