摘要
为提高槲皮素的水溶性,制备了O/W型吐温80-乙醇-花生油-水的微乳体系,考察了该体系对槲皮素的增溶效果,结果槲皮素的溶解度由4.8μg/mL增加到319.1μg/mL。在模拟人体胃液的条件下,测定槲皮素微乳对亚硝化反应的抑制活性。结果表明:槲皮素微乳对亚硝化反应具有较强的抑制作用,对亚硝胺合成的最大阻断率为89.28%,对亚硝酸钠的最大清除率为90.47%。
To improve the solubility of quercetin in aqueous solution,O/W microemulsion system containing tween 80-alcohol-peanut oil-water was prepared.The enhancing effect of microemulsion on the solubility of quercetin was preliminarily examined and solubility of quercetin increased from 4.8 to 319.1 μg/mL.Under the simulated condition of gastric, the inhibition of nitroso reaction by microemulsion of quercetin were studied.The results showed that the microemulsion of quercetin has strong effect on disconnecting ND...
出处
《天然产物研究与开发》
CAS
CSCD
2008年第1期12-15,共4页
Natural Product Research and Development
基金
黑龙江省教育厅重点项目(11511Z03)
关键词
槲皮素
微乳
增溶
亚硝化
quercetin
microemulsion
solubilization
nitrosamine
