期刊文献+

肌肽的生理活性及其检测方法研究进展 被引量:4

Physiological Activities and Determination Methods of Carnosine
下载PDF
导出
摘要 论文简述了肌肽的化学性质和物理特性,综述了肌肽具有的缓冲pH、螯合金属离子、抗氧化及抑制非酶糖基化等生理活性,阐述了比色法、高效液相色谱法、毛细管电泳法等肌肽的检测方法,对于深入研究肌肽的生理功能及其应用有一定的参考价值。 Carnosine (β-alanyl-L-histidine) is a naturally-occurring dipeptide that can provide buffering capacity,chelate metal ions and protect biomolecules from oxidation or glycation.The chemical and physical properties of carnosine and its determination methods were summarized.
出处 《天然产物研究与开发》 CAS CSCD 2008年第2期367-370,共4页 Natural Product Research and Development
关键词 肌肽 生理活性 检测方法 carnosine physiological activity detecting method
  • 相关文献

参考文献1

二级参考文献14

  • 1Hipkiss A R,Brownson C.A possible new role for the anti-aging peptide camosine.Cell Mol Life Sci,2000,57(5):207-210
  • 2Wang A M,Ma C,Xie ZH,Shen F.Use of carnosine as a natural antisenescence drug for human being.J Bid Chem,2000,65(7):869 -871.
  • 3Boldyrev A A.Carnosine as a modulator of endogenous Zn2 + effects.Trends Pharmacol Sci,2001,22:112-113
  • 4Pegova A,Abe H,Boldyrev A A.Hydrolysis of carnosine and related compounds by mammalian carnosinases.Comp Biochem Physiol B,2000,127(4):443-446
  • 5Dunnett M,Harris R C.High-performance liquid chromatographic determination of imidazole dipeptides,hisidine,1-methylhisdine and 3-methylhistidine in equine and camel muscle and individual muscle fibre.J.Chromatogr,1997,688:47-55.
  • 6Marlin D J,Harris R C.Carnosine content of the middle gluteal muscle in thoroughbred horses with relation to age,sex and training.Comp.Biochem.Physiol,1989,93:629-632.
  • 7Johnson P,Hammer J L.Histidine dipeptide levels in ageing and hypertensive rat skeletal and cardiac muscle.Comp.Biochem.Physiol,1992,103:981-984
  • 8Michelle S,Homing,Laura J,Blakemore.Endogenous mechanisms of neuroprotection:role of zinc,copper and carnosine.Brain Research,2000,852:56-61
  • 9Mcfarland G A,Holiday R.Differential response of embryonic stem cells and teratocarcinoma cells to carnosine.In Vitro cell Dev,1999,35 (1):15-16
  • 10Hipkiss A R,Preston J E,Himswreth D T.Pluripotent protective effects of carnosine,a naturally occurring dipeptide.Ann NY acad Sci,1998,854:37-53

共引文献4

同被引文献29

引证文献4

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部