非转流原位肝移植不同术式对麻醉管理的影响

Effects of Different Ways of Orthotopic Liver Transplantation without Venovenous Bypass on Anesthetic Management

目的比较非转流背驮式与经典式原位肝移植术(orthotopic liver transplantation,OLT)对麻醉管理的影响。方法回顾性分析2003年11月~2006年12月我院50例非转流OLT的临床资料,其中背驮式(A组)和经典式(B组)各25例,比较2组患者在围术期血流动力学、凝血状况、肝肾功能、内环境的改变及液体治疗等方面的异同。结果无肝期即刻A组平均动脉压(68±6)mm Hg显著高于B组(64±5)mm Hg(t=2.561,P=0.014),A组中心静脉压(5.4±3.3)mm Hg高于B组(3.5±2.3)mm Hg(t=2.362,P=0.022),A组心脏指数(3.7±0.8)L.min-1.m-2显著高于B组(3.2±0.6)L.min-1.m-2(t=2.500,P=0.016)。新肝期即刻A组平均动脉压(66±6)mm Hg明显高于B组(62±5)mm Hg(t=2.561,P=0.014),A组中心静脉压(8.4±4.0)mm Hg与B组(10.6±4.2)mm Hg无统计学差异(t=-1.897,P=0.064)。再灌注综合征的发生率A组(2/25,8.0%)低于B组(8...

Objective To compare the effects of piggyback and classic orthotopic liver transplantation (OLT) without venovenous bypass on anesthetic management. Methods A retrospective review was conducted on the clinical data of 50 cases of OLT without venovenous bypass performed from November 2003 to December 2006, including 25 piggyback (group A) and 25 classic (group B) OLT. The perioperative hemodynamics, hemostatic conditions, hepatic and renal functions, changes of internal environment, and fluid therapy were co...