摘要
目的探讨经尿道电切术联合术后表柔比星膀胱灌注治疗腺性膀胱炎的疗效。方法2000年1月～2006年1月,对130例腺性膀胱炎采用经尿道电切术,电切时切除所有病变黏膜及周边1cm正常膀胱黏膜,切除深度直达浅肌层。术后1周开始表柔比星膀胱灌注,每次50mg,每周1次,共8次,以后每月1次,持续2年。结果5例术后尿道狭窄,经定期扩张后治愈,余无并发症。98例症状消失,23例偶有尿路刺激症状,复查膀胱镜黏膜正常;9例复发,其中5例术后6～12个月出现非灌注后血尿,4例无症状定期复查,行膀胱镜检查见原位复发,活检病理确认后再次行经尿道电切术,术后更换灌注药物为羟基喜树碱,每次20mg,随访12个月,无复发。结论经尿道电切术联合术后有效化疗药物膀胱灌注治疗腺性膀胱炎,疗效满意,值得推广应用。
Objective To investigate the efficacy of transurethral electroresection combined with intravesical irrigation with epirubicin for cystitis glandularis.Methods From January 2000 to January 2006,130 patients with cystitis glandularis were treated with transurethral electroresection.The whole depth of diseased mucosa and adjacent normal mucosal tissues(1 cm away)were resected.One week after the operation,intravesical irrigation with epirubicin were carried out(50 mg per time,once a week for 8 weeks,and then on...
出处
《中国微创外科杂志》
CSCD
2008年第4期329-330,共2页
Chinese Journal of Minimally Invasive Surgery
关键词
腺性膀胱炎
经尿道电切术
Cystitis glandularis
Transurethral electroresection
