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ST/HR指数对介入术后再狭窄诊断的研究

USING ST/HR INDEX IN EXERCISE TEST TO DIAGNOSIS RESTENOSIS AFTER PCI
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摘要 目的:探讨心电图运动试验测定ST/HR指数诊断冠心病介入术后再狭窄。方法:对成功行冠脉介入治疗(PCI)的129例患者,在术后3~6个月进行随访,测量心电图运动试验ST/HR指数及常规ST段阳性标准诊断再狭窄,通过冠状动脉造影确定有无再狭窄,评价其诊断再狭窄的价值。结果:在入选的病例中,经冠脉造影证实在介入治疗后有75例发生再狭窄,再狭窄组和无再狭窄组间患者的性别、年龄、伴随疾病以及药物治疗情况无明显差异(P>0.05);再狭窄组和无再狭窄组血脂水平、空腹血糖、吸烟史、病变类型及病变血管支数有差异(P<0.05)。对患者运动试验时各项指标进行测量,再狭窄组的运动峰血压(收缩压)、心率血压乘积、ST段最大下降幅度、ST/HR指数与无再狭窄组对比,结果不同(P<0.05)。ST/HR指数诊断再狭窄的敏感性和特异性分别为52.0%、74.1%,与传统ST段标准(53.3%,66.7%)比较结果相似(P>0.05)。结论:应用ST/HR指数可作为诊断再狭窄的一种参考指标。 Objective:To study the sensitivity and specificity of ST/HR Index at the end of ECG exercise test on diagnosing restenosis after PCI.Method 129 patients who undergoing PCI successfully 3～6 months before were involved.Treadmill exercise test and ST/HR Index was measured just at the end of exercise test.All patients also accepted coronary angiography to be confirmed whether he/she had restenosis.the results of ST/HR Index and ST segment depression was evaluated.Result ST/HR Index in restenosis group is signif...
作者 侯瑞田 金凤表 孙砾贤 郝志敏 李春华 丁振江 王虹
机构地区 承德医学院附属医院心内科
出处 《承德医学院学报》 2006年第2期127-130,共4页 Journal of Chengde Medical University
关键词 介入治疗 再狭窄 运动试验 ST/HR指数 冠心病 percutaneous coronary intervention restenosis exercise stress test ST/HR Index
分类号 R543.3 [医药卫生—心血管疾病]
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参考文献13

  • 1[1]Gruentzig AR.Transluminal dilatation of coronary artery stenosis[J].Lancet,1978,(1):263-269.
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二级参考文献12

  • 1Gruntzig A.Transluminal dilatation of coronary artery stenosis[J].Lancet,1978,1(8 058):263-269.
  • 2Serruys PW,Luijlen HE,Beatt KJ,et al.Incidence of restenosis after successful coronary angioplasty:a time-related phenomenon.A quantitative angiographic study in 342 consecutive patients at 1,2,3 and 4 months[J].Circulation,1998,77(2):361-371.
  • 3Garzon PP,Eisenberg MJ.Functional testing for the detection of restenosis after percutaneous transluminal coronary angioplasty:a meta-analysis[J].Can J Cardiol,2001,17(1):41-48.
  • 4Hamasaki S,Abematsu H,Arima S,et al.A new predictor of restenosis after successful percutaneous transluminal coronary angioplasty in patients with multivessel coronary artery disease[J].Am J Cardiol,1997,80(4):411-415.
  • 5Okin PM,Kligfield P.Heart rate adjustment of ST segment depression and performance of the exercise electrocardiogram:critical evaluation[J].Am Coll Cardiol,1995,25(7):1 726-1 729.
  • 6Lytle BW,McElroy D,McCarthy P,et al.Influence of arterial coronary bypass grafts on the mortality in coronary reoperations[J].J Thorac Cardiovasc Surg,1994,107(3):675-682.
  • 7Kimura T,Tamura T,Yokoi H,et al.Long-term clinical and angiographic follow-up atter placement of Palmaz-Schatz coronary stent:a single center experience[J].J Interv Cardiol,1994,7(2):129-139.
  • 8Kastrati A,Schomig A,Diets R,et al.Time course of restenosis during the first year after emergency coronary stenting[J].Circulation,1993,87(50):1 498-1 505.
  • 9Viik J,Lehtinen R,Turjanmaa V.The effect of lead selection on traditional and heart rate-adjusted ST segment analysis in the detection of coronary artery disease during exercise testing[J].Am Heart J,1997,134(3):488-494.
  • 10Papazoglou N,Kalpoyiannakis I,Papazoglou S.Determinants of exercise induced ST segment depression in patients with coronary artery disease:a multivariate approach[J].Angiology,1997,48(2):135-139.

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承德医学院学报
2006年 第2期

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