摘要
在无溶剂的条件下,香豆素-3-甲酰氯与等当量的各种酚钠在室温下研磨可快速地得到香豆素-3-甲酸芳酯(1a～1k)。该法与传统的溶液法相比具有无有机溶剂污染,反应速度快,产率高和后处理简单等诸多优点。
when coumarin-3-formyl chloride and equivalent of various sodium phenolates were grinded together under solventless and room-temperature condition, coumarin-3-carboxylates would be yielded rapidly. This synthetic method had advantages of no organic solvent pollution, high reaction speed, high yield and simple aftertreatment procedure compared with traditional solution method.
出处
《甘肃农业大学学报》
CAS
CSCD
2005年第3期345-347,共3页
Journal of Gansu Agricultural University
基金
西北师范大学科技创新工程(NWNU-KJCXGC-02-08)
甘肃省自然科学基金(ZS021-A25-006-Z)
甘肃省环保基金(GH2002-16)资助项目
关键词
香豆素
无溶剂
研磨
合成
coumarin
solvent-free
grinding
synthesis
