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原因不明性不孕的助孕方式的探讨 被引量:2

Retrospective Study of Artificial Reproductive Technique in Unexplained Infertility
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摘要 目的:探讨不同助孕技术对原发性或继发性原因不明不孕(UI)的治疗结局。方法:回顾分析2001年1月~2006年4月我院诊断为UI并采用助孕技术治疗的患者共90例:原发性UI47例(A组),继发性UI43例(B组)。两组患者分别进行了宫腔内人工授精(IUI)和体外受精(IVF)治疗。结果:两组IUI的累积妊娠率分别为A组20.4%,B组23.2%。促排卵周期方案中的CC/HMG/HCG+IUI和HMG/HCG+IUI方案的妊娠率均显著高于自然周期和CC+IUI;第2和第3个IUI周期的妊娠率显著高于第1周期;≥4个周期的IUI均无妊娠。在IVF中,A组的取消周期数、临床妊娠率、获卵数、受精率和胚胎种植率显著低于B组,受精率<30%的周期数显著高于B组。在B组中,IUI和IVF治疗中各出现一例异位妊娠。结论:促排卵+IUI能纠正部分UI患者的轻微病因,是UI的首选治疗方法。原发性UI患者行IVF时,卵子不受精或受精率明显下降的风险明显高于继发性UI;继发性UI的病因可能与输卵管功能和/或子宫内膜容受性下降有关。 Objective:To analyze the selection of artificial reproductive techniques for unexplained infertility(UI).Methods:Ninety couples were diagnosed UI and divided into 2 groups:group A(primary UI)and group B(secondary UI),and received the treatment of intrauterine insemination(IUI)and in vitro fertilization(IVF),respectively.Results:The cumulative pregnancy rate of IUI was 20.4% in group A and 23.2% in group B.The pregnancy rate(PR)in CC/HMG/HCG+IUI and HMG/HCG+IUI cycles was higher than in CC+IUI and natural cy...
出处 《华西医学》 CAS 2007年第4期768-770,共3页 West China Medical Journal
关键词 人工授精 体外受精—胚胎移植 insemination intrauterine controlled ovarian stimulation unexplained primary secondary IVF-ET
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