白花蛇舌草化学成分的研究

Chemical constituents from Hedyotis diffusa

对白花蛇舌草(Hedyotis diffusa)的化学成分进行研究.采用甲醇提取,石油醚、氯仿-甲醇(V/V为1∶1)、甲醇-水(V/V为1∶1)溶剂划段,多种分离材料进行反复分离纯化,根据化合物的理化性质和光谱数据鉴定其结构.从其氯仿-甲醇(V/V为1∶1)部分分离鉴定了7个化合物:3-甲氧基-5,7-二羟基-黄酮醇(Ⅰ)、10-乙酰基鸡屎藤甙(Ⅱ)、车叶草甙(Ⅲ)、5,7,4′-三羟基-黄酮醇(Ⅳ)、熊果酸(Ⅴ)、胡萝卜苷(Ⅵ)、β-谷甾醇(Ⅶ).化合物Ⅰ,Ⅱ首次从该植物中分离得到.

From the Hedyotis diffusa seven known compounds were isolated.Their structures were determined as 3-methoxy-5,7-dihydroxy flavonol(Ⅰ),10-acetyl scandoside(Ⅱ),asperuloside(Ⅲ),5,7,4′-trihydroxy flavonol(Ⅳ),ursolic acid(Ⅴ),daucosterol(Ⅵ),β-Stiosterol(Ⅶ).