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慢性牙周炎患者EB病毒Real-Time PCR检测

Determination of Epstein-Barr virus DNA in patients with chronic periodontitis
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摘要 目的:探讨EB病毒(EBV)感染水平与慢性牙周炎(CP)的关系。方法:采集30例CP患者深牙周袋标本及牙龈组织,记录牙周袋探诊深度、附着丧失水平、牙龈指数,real-time PCR法检测EBV DNA。12例正畸、8例腭裂修补术患者作正常对照。结果:CP组EBV DNA检出率高于正常对照组(P<0.05)。CP组深牙周袋EBV DNA检出率高于牙龈组织(P<0.05),但2者EBV DNA水平差异无统计学意义(P>0.05)。CP患者深牙周袋EBVDNA水平与牙龈指数、牙周袋深度和附着丧失水平均不相关(rs分别为0.34、0.64、0.71,P均>0.05)。结论:EBV可能与CP有关,深牙周袋是EBV主要存在部位。 Aim:To explore the relationship between Epstein-Barr virus and chronic periodontitis(CP).Methods:Deep periodontal pocket samples and gingival tissues were obtained from 30 CP patients,The Epstein-Barr virus DNA were determined by real-time PCR,and pocket probing depth,clinical attachment loss and gingival index were recorded.20 healthy people were the normal control.Results:The identification rate of EBV DNA of CP group was higher than that of the control(P<0.05).In CP group,the identification rate of EB...
作者 刘兴国 耿建华 管泽民
机构地区 河南省人民医院口腔科
出处 《郑州大学学报（医学版）》 CAS 北大核心 2007年第4期740-742,共3页 Journal of Zhengzhou University(Medical Sciences)
关键词 EB病毒 慢性牙周炎 REAL-TIME PCR Epstein-Barr virus chronic periodontitis real-time PCR
分类号 R781.42 [医药卫生—口腔医学]
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参考文献11

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共引文献4

郑州大学学报（医学版）
2007年 第4期

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