摘要
脂联素是一种脂肪细胞特异性分泌蛋白,大量特异表达于脂肪组织,低血浆脂联素水平与冠状动脉疾病(CAD)有关。曾有建议认为高分子量(HMW)脂联素较脂联素总量具有更重要的血管保护意义。为了确立HMW脂联素的临床相关意义,测定了149例CAD患者的血清HMW脂联素水平。结果发现血管痉挛性心绞痛(3.4±2.4mg/L,P<0.01)、
Adiponectin is an adipocyte-specific secretory protein that is highly and specifically expressed in adipose tissue, and low plasma levels of adiponectin are associated with coronary artery disease(CAD). It has been suggested that high molecular weight(HMW) adiponectin is more important for vascular protection than total amount of adiponectin. To establish the clinical relevance of HMW adiponectin, we measured its serum levels in 149 patients with CAD. The levels were lower in vasospastic angina pectoris(3.4...
