摘要
左室(LV)功能障碍伴房颤(AF)患者的最佳治疗尚未确定。与LV功能正常或轻度降低的患者相比,对射血分数(EF)明显降低的患者维持窦性心律是否获益更大尚不清楚。AFFIRM(节律治疗房颤随访调查)研究中比较了以下两种策略:"节律控制",即维持窦性心律,主要使用抗心律失常药物;"心率控制",允许AF持续存在或反复发生但控制心室率。
Optimal treatment for patients with atrial fibrillation(AF) and left ventricular(LV) dysfunction is not well defined. It is unclear if sinus rhythm is of greater benefit in patients with significantly reduced ejection fraction(EF) than in patients with normal or mildly depressed LV function. The Atrial Fibrillation Follow-up Investigation of Rhythm Management(AFFIRM) study compared 2 treatment strategies: " rhythm control," attempting to maintain sinus rhythm, principally with antiarrhythmic drugs, and " ra...
