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原发性高血压患者中压力反射敏感性与左室形态及舒张功能相关

Baroreflex sensitivity correlates with left ventricular morphology and diastolic function in essential hypertension
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摘要 目的:动脉性高血压是心脏器质损害(包括形态和功能上的改变)的常见原因。对心率的自发性压力反射敏感性(BRS)控制是维持血压稳定的关键机制,在高血压患者中此作用削弱。本研究拟评价BRS与左室形态及功能之间的联系。方法:对224例高血压患者(125例男性;年龄47.8±10.8岁,x±s)与51例血压正常的对照受试者(25例男性;年龄45.7±12.5岁)进行了比较。 OBJECTIVES: Arterial hypertension is a common cause of cardiac organ damage, inducing morphological and functional modifications. Spontaneous baroreflex sensitivity (BRS) control of the heart rate is a key mechanism of blood pressure homeostasis, and is impaired in patients with hypertension. This study sought to assess the association between BRS and left ventricular morphology and function. METHODS: We studied 224 hypertensive patients (125 men; aged 47. 8 ±10. 8 years, mean±SD) compared with 51 normotens...
机构地区 Hypertension Unit
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