摘要
房颤(AF)为冠状动脉搭桥术(CABG)后常见的并发症。尽管心脏外科术后AF发生较普遍,但其病理生理学机制仍未完全阐明。作者先前的研究表明,年龄及左房扩大为术后发生AF的独立预测因素。因此,本研究试图确定在术后发生AF的患者中是否发生细胞特性改变,如心肌纤维化和(或)心肌细胞肥大。对行择期CABG术的患者在心房切开时获取右心耳组织。
Atrial fibrillation(AF) is a common complication after coronary artery bypass graft(CABG) surgery. Despite the prevalence of AF occurring after cardiac surgery, its pathophysiology is incompletely understood. Our previous study demonstrated that age and left atrial enlargement were independent predictors of postoperative AF. Accordingly, the purpose of this study was to determine whether cellular changes such as fibrosis and/or hypertrophy occurred in the atrium in patients who subsequently developed postop...