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无慢性肾脏疾病的老年人群中半胱氨酸蛋白酶抑制剂C对心血管和肾脏结局的预测价值

Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease
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摘要 背景:半胱氨酸蛋白酶抑制剂C是肾脏功能的可选指标,其在不符合慢性肾脏疾病诊断标准犤估计肾小球滤过率(GFR)≥60ml/(min·1.73m2)犦的老年人群中可能具有预后预测意义。目的:在无慢性肾脏疾病的老年人群中评价半胱氨酸蛋白酶抑制剂C作为死亡、心血管疾病和新发慢性肾脏疾病的生物标记物的价值。设计:队列研究。地点:心血管健康研究, Background: Cystatin C is an alternative measure of kidney function that may have prognostic importance among elderly persons who do not meet standard criteria for chronic kidney disease(estimated glomerular filtration rate[GFR] ≥ 60 mL/min per 1.73 m2). Objective: To evaluate cystatin C as a prognostic biomarker for death, cardiovascular disease, and incident chronic kidney disease among elderly persons without chronic kidney disease. Design: Cohort study. Setting: The Cardiovascular Health Study, a popula...
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