有机磷农药中毒解救及对过氧化脂、肾功能的影响

Effects of organophorus pesticide poisoning and its rescue

目的:探讨有机磷农药对过氧化脂质(Lpo)、肌酐(Cr)、尿素氮(Bun)的影响。方法采用敌百虫急性中毒模型,测定其中毒及解救过程中Lpo、Cr、Ache含量.结果有机磷农药中毒及注射阿托品解救后,Lpo明显增高,使用解磷定(Pam)30min后,Lpo明显降低;Lpo变化与Ache呈负相关性;Cr、Bun在中毒及解救中变化很小.结论有机磷农药中毒时Lpo有明显增高,Lpo变化与Ache呈负相关性.

Objective to explore the effects of orgemophorus pesticide on lipid peroxidase(Lpo),creatinine(Cr)andblood urea nitrpogen(Bun).methods the animal samples of acutely poisoned dipterex poisoned and rescued were used to measure the content of lpo.cr and cholinesterase(Che)in the poisoning and rescue course.Results lpo was higher significantly in the poisoning and rescue with the injection of atropine,and lpo was lower significantly with the action of pralidoxime(PAM)after 30 minutes;the negative correlation be...