摘要
背景:50岁以上成人中12%受到外周动脉疾病(PAD)的影响。传统治疗方法仅能稍稍改善症状。目的:观察血管紧张素转换酶抑制剂对PAD患者行走能力的影响。设计:一项随机、双盲、安慰剂对照的临床试验,始于2003年3月,终止于2005年1月。
Background: Peripheral arterial disease(PAD) affects up to 12% of adults older than 50 years of age. Conventional therapies have only modest effects in improving symptoms. Objective: To examine the effects of angiotensin-converting enzyme inhibition on walking ability in patients with PAD. Design: Randomized,double-blind,placebo-controlled trial initiated in March 2003 and completed in January 2005. Setting: The Alfred Hospital,Melbourne,Australia. Participants: 40 older adults with symptomatic PAD and no h...
