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急性心肌梗死患者及时溶栓后行冠状动脉血管成形术是否可改善微血管灌注和左心室功能?

Does coronary angioplasty after timely thro-mbolysis improve microvascular perfusion and left ventricular function after acute myocardial infarction?
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摘要 背景:近期的数据显示,对于稳定的溶栓后ST段抬高型心肌梗死(STEMI)患者,予经皮冠状动脉介入治疗(PCI)优于不予PCI治疗或因缺血行补救性PCI。对这些结果仍需寻求病理生理学方面的解释。 Background: Recent data show that percutaneous coronary intervention(PCI) in patients with stable postthrombolytic ST-segment elevation myocardial infarction(STEMI) is better than no PCI or ischemia-guided PCI. These results still have to find a pathophysiologic explanation. We hypothesized that complete mechanical recanalization of infarct-related artery improves clinical benefits of thrombolysis as a result of more preserved and better perfused coronary microcirculation. To test this hypothesis,we studied...
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