摘要
背景:胎球蛋白A是一种肝脏分泌的多功能蛋白质,能抑制营养不良性血管和瓣膜的钙化。较低的血清胎球蛋白A水平与终末期肾病患者的血管钙化有关。在其他患者中胎球蛋白A是否与血管钙化相关。
BACKGROUND -Fetuin-A is a multifunctional hepatic secretory protein that inhibits dystrophic vascular and valvular calcification. Lower serum fetuin-A concentrations are associated with valvular calcification in persons with end-stage renal disease. Whether fetuin-A is associated with valvular calcification in other patient populations is unknown. METHODS AND RESULTS -We evaluated the associations among serum fetuin-A concentrations,mitral annular calcification,and aortic stenosis in 970 ambulatory persons ...
