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对患有冠心病的高血压患者大幅降压是否有危险? 被引量:1

Dogma disputed:Can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?
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摘要 背景:由于冠状动脉灌注主要发生在心动周期的舒张期,如果舒张压低于临界水平则冠心病(CAD)患者发生冠状动脉事件的风险增高。目的:确定在此类人群中低血压是否与增高的死亡率和发病率有关。 Background: Because coronary perfusion occurs mainly during diastole, patients with coronary artery disease(CAD) could be at increased risk for coronary events if diastolic pressure falls below critical levels. Objective: To determine whether low blood pressure could be associated with excess mortality and morbidity in this population. Design: A secondary analysis of data from the International Verapamil-Trandolapril Study(INVEST), which was conducted from September 1997 to February 2003. Setting: 862 sites...
机构地区 Division of Cardiology
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