摘要
背景:直至最近,磁共振成像(MRI)技术的发展才使在体检验人类调脂治疗时脂质消退的假说成为可能。试验设计:颈动脉斑块组成研究是一项前瞻性随机研究,旨在在体检验脂质消退假说。纳入患有冠状动脉疾病(CAD)
Background: In vivo testing of the lipid depletion hypothesis in human beings during lipid-modifying therapy has not been possible until recent developments in magnetic resonance imaging(MRI). Trial Design: The Carotid Plaque Composition Study is a prospective, randomized study designed to test the lipid depletion hypothesis in vivo. One hundred twenty-three subjects with coronary artery disease(CAD) or carotid disease and with levels of apolipoprotein B ≥120 mg/dL(low-density lipoprotein levels 100-190 mg/...
