摘要
背景:本研究拟验证如下假说,即西地那非慢性治疗对于艾森门格综合征致严重肺动脉高压患者与其他无心内分流的严重特发性肺动脉高压患者具有同样的功能和血流动力学作用。方法:进行一项前瞻性。
Background: To test the hypothesis that chronic sildenafil treatment has similar functional and hemodynamic effects in patients with severe pulmonary arterial hypertension due to Eisenmenger syndrome as those due to idiopathic pulmonary arterial hypertension without intracardiac shunts. Methods: A prospective open-label study was carried out to compare the effects of sildenafil on the pulmonary hemodynamics between two groups of patients with severe pulmonary hypertension and similar baseline functional cap...