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辛伐他汀治疗颈动脉粥样硬化疗效观察 被引量:3

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摘要 目的采用颈动脉超声定量评价辛伐他汀治疗颈动脉粥样硬化的疗效。方法治疗组给予辛伐他汀20 mg/d口服,对照组给予肠溶阿司匹林100 mg/d口服,共6个月。所有患者于服药前后检查相应生化指标,应用HPSONOS5500型彩色多普勒超声测定颈动脉内膜-中层厚度(IMT)及斑块面积,计算斑块数量。结果治疗组治疗后IMT变薄,斑块面积缩小,斑块数量无明显改变,总胆固醇、低密度脂蛋白水平均明显降低,肝肾功能无明显差异;对照组各指标治疗前后比较无显著性改变。结论坚持服用他汀类药物,可以达到稳定与消退斑块的作用。
作者 吕大军
出处 《现代中西医结合杂志》 CAS 2007年第7期912-913,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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