期刊文献+

瑞巴派特治疗胃溃疡的疗效观察 被引量:5

Clinicial Observation on Rebamipide in Treating Patients with Gastric Ulcer
下载PDF
导出
摘要 目的:探讨瑞巴派特治疗胃溃疡的疗效。方法:将93例患者随机分为A、B、C三组,A组给予瑞巴派特+法莫替丁+阿莫西林+甲硝唑;B组给予铝碳酸镁+法莫替丁+阿莫西林+甲硝唑;C组给予硫糖铝+法莫替丁+阿莫西林+甲硝唑。结果:在总S期和S2期获得率以及溃疡直径减小程度等A组明显高于B、C两组。结论:瑞巴派特是促进溃疡愈合方面疗效较高的药物。 Objective:To study the effect of rebamipide on the patients with gastric ulcer.Method:93 examples were divided into A、B、C three groups at random,A: rebamipide+famotidine+amoxicillin+metronidazole;B: hydrotalcite+ famotidine+amoxicillin+metronidazole;C: sucralfate+ famotidine+amoxicillin+metronidazole.Result:group A obviously prior than group B and C in the reduce degree of gastic ulcer diameter in phase S.Conclusion:Rebamipide is valuable drug in the clinical treatment with gastric ulser.
出处 《河北医学》 CAS 2007年第3期310-312,共3页 Hebei Medicine
关键词 瑞巴派特 胃溃疡 Rebamipide Gastriculcer
  • 相关文献

参考文献6

  • 1[1]HarumaK,ItoM.Review article:clinical significance of mucosal-protective agents:acid,inflammation,carcinogenesis and rebamipide[J].Aliment Pharmacol Ther,2003,1:153-9.
  • 2[2]Naito Y,Kajikawa H,Mizushima K,et al.Rebamipide,a gastro-protective drug,inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells:association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression[J].Dig Dis Sci,2005,1:S104-12.
  • 3[3]Sakurai K,Sasabe H,Koga T,et al.Mechanism of hydroxyl radical scavenging by rebamipide:identification of mono-hydroxylated rebamipide as a major reaction product[J].Free Radic Res,2004,38(5):487-94.
  • 4[4]Watanabe T,Higuchi K,Taira K,Sasaki E,et al.Rebamipide reduces delay in gastric ulcer healing in cyclooxygenase-2-deficient mice[J].Dig Dis Sci,2005,1:S63-9.
  • 5孙菁,袁耀宗,施尧,戈之铮,钟良,陈世耀,邹多武,王兴鹏.瑞巴派特联合法莫替丁治疗活动期胃溃疡61例[J].中国临床药学杂志,2006,15(2):70-73. 被引量:6
  • 6[6]Fujiwara Y,Higuchi K,Tominaga,K,et al.Effects of rebamipide,a gastro-protective drug on the Helicobacter pylori status and inflammation in the gastric mucosa of patients with gastric ulcer:a randomized double-blind placebo-controlled multicentre trial[J].Aliment Pharmacol Ther,2003,1:146-52.

二级参考文献6

  • 1Tarnawski AS,Chai J,Pai R,et al.Rebamipide activates genes encoding angiogenic growth factors and Cox2 and stimulates angiogenesis:a key to its ulcer healing action[J]? Dig Dis Sci,2004,49(2):202.
  • 2Sakurai K,Osaka T,Yamasaki K.Rebamipide reduces recurrence of experimental gastric ulcers:role of free radicals and neutrophils[J].Dig Dis Sci,2005,50(Suppl 1):S90.
  • 3Szabo S,Vincze A.Growth factor in ulcer healing:Lessons from recent studies[J].J Physiol,2000,94(1):77.
  • 4Dixon MF,Genta RM,Yardley JH,et al.Classification and grading of gastritis-the updated sydney system[J].Am J Surg Pathol,1996,20(10):1161.
  • 5Malfertheiner P,Megrand F,O' Morain C,et al.Current European Concepts in the management of Helicobacter pylori infection-the Maastricht Consensus Report[J].Eur J Gastroenterol Hepatol,1997,9(1):1.
  • 6幽门螺杆菌若干问题的共识意见[J].胃肠病学,2000,5(1):5-7. 被引量:74

共引文献5

同被引文献23

引证文献5

二级引证文献59

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部