血管淋巴样增生伴嗜酸性粒细胞增多症一例报道及文献复习

One report of angiolymphoid hyperplasia with eosinophilia and review of available literature

目的报道1例血管淋巴样增生伴嗜酸性粒细胞增多症(ALHE),并结合文献对其临床病理学特点进行探讨。方法应用常规HE染色方法,分析和观察1例ALHE的临床资料和组织学形态。结果该病例以枕后包块就诊,组织学主要表现为血管的增生,增生的血管内皮细胞呈特征的上皮样,可内衬血管腔,突入血管腔内生长,或在血管旁间质内呈实性片状或条索状生长。间质伴有大量的嗜酸性粒细胞为主的炎细胞浸润,而淋巴细胞的漫润相对不明显。结论ALHE主要表现为血管内皮细胞的上皮样增生,以上皮样血管瘤进行命名较为妥当。ALHE与Kimura病应为两种性质不同的疾病。

Objective To Report one case of Angiolymphoid Hyperplasia with Eosinophilia (ALHE) and Investigate Its Clinicopathologic Features by Combining with Available Literature. Methods Evaluationg of Clinical Data and Histopathologic Features was Performed in One case of ALHE by HE Staining and Light Microscopy. Results This Case Presented as a mass at the occipital.Histologically,It Mainly Showed Prominent Proliferation of Vessels.The Vessels were Lined by Epithelioid Endothelial Cells.The Endothelial Cells also Proliferated within the Lumen and Grew in Sheets or Cords Adjacent to the Vessel Walls.Large Number of Eosinophils Aggregated around the Vessels.Relatively,the Aggregatting of lymphoid cells wasn't Prominent. Conclusions ALHE Mainly Displays Epithelioid Proliferation of Vessel Endothelial Cells, Epithelioid Hemangioma is Appropriate to the naming of this disease. ALHE and Kimura's disease are Two Distinctive Entities.