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它莫西芬诱导乳腺癌MCF-7细胞自噬的比较蛋白质组学研究

Proteomics Analysis of Tamoxifen-induced Autophagic MCF-7 Cells
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摘要 The differentially expressed proteins between normal and tamoxifen-induced autophagic MCF-7 cells were studied by 2-DE combining with mass spectrometric analysis.Totally,there were 668±99 and 550±97 protein spots detected in the 2-DE maps from normal and autophagic MCF-7 cells respectively,among which 5 changed protein spots were identified by the Q-TOF MS/MS and database search. The differentially expressed proteins between normal and tamoxifen-induced autophagic MCF-7 cells were studied by 2-DE combining with mass spectrometric analysis.Totally,there were 668±99 and 550±97 protein spots detected in the 2-DE maps from normal and autophagic MCF-7 cells respectively,among which 5 changed protein spots were identified by the Q-TOF MS/MS and database search.
作者 娄雅欣 钟丽君 杨彬 陈丽娜 刘丹 邹霞娟 彭嘉柔
机构地区 北京大学医药卫生分析中心 北京大学人类疾病基因研究中心
出处 《分析测试学报》 CAS CSCD 北大核心 2007年第z1期78-79,共2页 Journal of Instrumental Analysis
关键词 PROTEOMICS Two dimensional gel electrophoresis Mass spectrometry AUTOPHAGY Proteomics Two dimensional gel electrophoresis Mass spectrometry Autophagy
分类号 O657-55 [理学—分析化学]
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参考文献6

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分析测试学报
2007年 第z1期

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