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液质联用分析美伐他汀的有关物质 被引量:2

Study on Relative Substances of Mevastatin by HPLC-MS
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摘要 HPLC-ESI MS/MS method for relative substances of Mevastatin was established.An Agilent C18 column 250×4.6mm;Mobile phase: acetonitrile-0.05% formic acid (70:30),flow rate 1.0 mL/min,and λ238 nm;MS and MS/MS spectra of sample and relative substances were obtained,approximately speculated the structure of relative substances,providing useful information for study and quality control of Mevastatin. HPLC-ESI MS/MS method for relative substances of Mevastatin was established.An Agilent C18 column 250×4.6mm;Mobile phase: acetonitrile-0.05% formic acid (70:30),flow rate 1.0 mL/min,and λ238 nm;MS and MS/MS spectra of sample and relative substances were obtained,approximately speculated the structure of relative substances,providing useful information for study and quality control of Mevastatin.
出处 《分析测试学报》 CAS CSCD 北大核心 2007年第z1期84-86,共3页 Journal of Instrumental Analysis
关键词 Mevastatin LC-MS/MS Relative substances Mevastatin LC-MS/MS Relative substances
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参考文献2

  • 1[1]KOCUAN A,GRAHEL R,ZUPANCIC L-KRALJ L L.[J].Acta chim Slov,2006,53:464-468.
  • 2[2]BP2004 monograph 1192-1193.

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