摘要
目的:研究OLIG2和GFAP在少突胶质细胞肿瘤组织病理学诊断中的作用。方法:应用免疫组织化学方法检测28例少突胶质细胞肿瘤、9例星形细胞瘤的OLIG2和GFAP表达情况。结果:免疫组织化学示:少突胶质细胞肿瘤细胞100%阳性;星形细胞瘤细胞56%OLIG2阳性;星形细胞瘤100%GFAP阳性,少突胶质细胞肿瘤中的少突胶质细胞瘤成份46%呈散在和灶状GFAP阳性。结论:OLIG2不是少突胶质系细胞的特异抗体。OLIG2与GFAP联合使用对少突胶质细胞肿瘤的诊断有一定价值。
Objective:To study diagnostic effects of OLIG2 and GFAP on oligodendrogliomas.Methods:Expressions o f OLIG2 and GFAP in 28 oligodendrogliomas and 9 astrocytoma were measured by immunohistochemistry method.Results: OLIG2 was positive in 100% of oligodendrogoliomas cell and 56% of astrocytoma respectively.Positive of GFAP was in 100% of astrocytoma and 46% of oligodendrogliomas.Conclusions:OLIG2 is not a specific antibody for the diagnosis of ologodendrogliomas but OLIG2 associated with GFAP has a diagnostic value.
出处
《青海医药杂志》
2007年第8期2-5,共4页
Qinghai Medical Journal
