摘要
目的评价国产头孢美唑钠治疗急性呼吸道感染的临床疗效和安全性。方法采用随机、双盲、对照试验的方法,治疗42例急性呼吸道感染患者(试验组20例、对照组22例)。试验药为注射用头孢美唑钠,对照药为注射用进口头孢美唑钠(先锋美他醇),1g/次,每日2次。疗程5~12天。结果试验组临床有效率和临床痊愈率分别为90·00%和25·00%,对照组临床有效率和临床痊愈率分别为86·36%和45·45%;试验组细菌清除率为100·00%,对照组细菌清除率为100·00%,各项指标比较差异均无显著性意义(P>0·05);安全性评价表明试验组与对照组的不良反应发生率分别为16·67%与8·33%,差异无统计学意义(P>0·05),未见严重不良反应。结论国产头孢美唑钠是治疗呼吸道感染安全、有效的抗菌药物。
ObjectiveTo evaluate the clinical efficiency and safety of domestic-made Cefmetazole Sodium to treat acute respiratory infection. MethodsA random, double blind and case controlled study was conducted to treat 42 cases of acute respiratory infection, consisting of a trial group (20 patients treated by domestic Cefmetazole Sodium) and a control group (22 patients treated by imported Cefmetazole Sodium). The dosage of these antibiotics was 1g/each time, twice a day, and the course of treatment was 5~12 days. R...
出处
《实用医院临床杂志》
2008年第2期61-63,共3页
Practical Journal of Clinical Medicine
关键词
头孢类美唑钠
呼吸道感染
Cefmetazole Sodium
Respiratory infection
