摘要
目的观察风湿性心脏病(RHF)心力衰竭(HF)急性加重时心肌肌钙蛋白I(cTnI)水平及其与心功能的相关性。方法应用微粒子化学发光法测定42例RHF患者的血清cTnI水平及用超声心动图测量左心室射血分数(LVEF),并与对照组比较。结果RHF患者HF急性加重时患者血清cTnI水平显著高于对照组(0.311±0.378vs0.013±0.009ng/ml,P<0.001),RHF组中17例血清cTnI水平升高,且cTnI水平与LVEF呈负相关(P<0.01);RHF组中血清cTnI水平高者6个月死亡率29.4%,而血清cTnI水平正常者为4.0%(P<0.05)。结论RHF患者HF急性加重时cTnI水平升高,其升高程度与HF严重程度相平行,对判断预后有一定意义。
Objective To observe and Analysis the level of serum cardiac troponin I(cTnI) and it s correlation with cardiac function of the patients with severity of rheumatic heart-failure.Methods Serum cTnI was measured in 42 patients with rheumatic heart-failure(RHF group) and 40 cases with no heart disease(control group) by microsome chemiluminescence method and left ventricular ejection function(LVEF) was detected in both groups by echocardiography.Results The serum level of cTn I in RHF group was significantly hi...
出处
《济宁医学院学报》
2008年第1期20-22,共3页
Journal of Jining Medical University
关键词
心脏病风湿性
心力衰竭
肌钙蛋白
心功能
rheumatic heart-failure
heart-failure
cardiac troponin
cardiac function
