免疫佐剂作用机制及CpG ODN作为新型佐剂的研究

The Reactive Mechanism of Immunoadjuvant and CpG ODN as a New Type of Immunoadjuvant

免疫佐剂通过免疫调节作用等5种方式发挥功能,借助佐剂的非抗原特异性的多克隆激活是天然免疫细胞可能的作用机制.大部分佐剂通过直接参与天然免疫事件而间接/直接影响获得性免疫应答,不同的佐剂可针对不同的事件发挥作用.CpG ODN作为佐剂的优势在新近的研究中被逐渐发现.

Immunoadjuvant functions through five major ways such as immune regulation,multi-activation by immnoadjuvant s irrantigen specialty may possibly the reactive mechanism in natural immune cells.Most adjuvant indirectly/directly affects acquired immune responses through directly participate in natural immune events,different adjuvant functions to vary events.CpG ODN s advantages as adjuvant is gradually discovered in recent researches.