克咳胶囊质量标准研究

Studies on quality standard of Keke Capsule

目的建立克咳胶囊的质量标准。方法对罂粟壳、甘草、苦杏仁进行薄层鉴别,采用HPLC法对麻黄碱进行含量测定。结果薄层鉴别重现性好;含量测定方法稳定,平均回收率为100.70%,精密度RSD为1.93%,重复性RSD为2.24%。结论薄层鉴别与含量测定方法稳定、简单,可行,重现性好。

OBJECTIVE The formulation of a standard for quality control of Keke Capsule.METHODS Pericarpium papaveris,Radix glycyrrhizae,Semen armeniacae amarum were identified by TLC and Herba Ephedrae was determined by RP-HPLC. RESULTS The methods of the chromatographic condition were reproducible;The peak area of Ephedrine hydrochoride was stable in 3 hours,the average recovery rate was 100.698%.RSD of precision was 1.93%,RSD of reproducibility was 2.24%.CONCLUSION CONCLUSION: The methods established are stable,simp...