期刊文献+

药物控制释放中的自组装聚合物微粒研究进展

Self-assembly polymers in drug delivery system
下载PDF
导出
摘要 介绍了两亲型嵌段共聚物、憎水链上接枝亲水链的接枝共聚物及聚电解质自组装的AB嵌段共聚物的结构、制备、作用机理及其在药物控制释放方面的应用,指出具有特殊结构、溶液中可自组装成相应形貌的高分子乳胶微球在此领域显示出巨大的优越性。 The structure,preparation and the action mechanism of amphiphilic block copolymers,graft copolymers and AB-typed block copolymers by polyelectrolyte self-assmbly and their application in drug delivery system are introduced in this paper.It is pointed out that the polymers particles with photo or electric performance,which can be self-assembled into definite morphology in solutions display great superiorities in this field.
出处 《现代化工》 CAS CSCD 北大核心 2006年第z1期116-118,共3页 Modern Chemical Industry
关键词 聚合物乳胶粒 自组装 药物输送系统 polymer colloidal particles self-assembly drug delivery system
  • 相关文献

参考文献25

  • 1[1]Cannizzaro S M,Langer R S.Polymeric systems for controlled drug release[J].Chem Rev,1999,99:3181-3198.
  • 2[2]Mathoeitz E.In encyclopaedia of controlled drug delivery[M].New York:John wilely and Sons,1999.
  • 3[3]廖工铁.靶向给药试剂[M].成都:四川科技出版社,1997.
  • 4[5]Kawashima Y.Nanoparticulate systems for improvetl drug delivery[J].Adv Drug Deliv Rev,2001,47:1-2.
  • 5林贤福 陈志春 吕德水.大分子自组装及其应用的研究与进展[J].高分子材料科学与工程,2000,16(4):5-7.
  • 6[7]Yang L,Alexandridis P.Physicochemical aspects of drug delivery and release from polymer-based colloids[J].Curr Opin Colloid In,2000,5:132-143.
  • 7[8]Allen C,Maysinger D,Eisenberg A.Nano-engineering block copolymer aggregates for drug delivery[J].Colloids Surfaces B,1999,16:3-27.
  • 8[9]Vandermeulen A R,Guido W M,Klok H A.Advanced drug delivery devices via self-assembly of amphiphilic block copolymers[J].Adv Drug Deliv Rev,2001,53:95-108.
  • 9[10]Iijima M,Nagasaki Y,Okada T,et al,Core-polymerized reactive micelles from heterotelechelic amphiphilic block copolymers[J].Macromolecules,1999,32:1140-1146.
  • 10[11]Thurmond K B,Kowalewski T,Wooley K L.Water-soluble knedel-like structures:The preparation of shell-cross-linked small particles[J].J Am Chem Soc,1996,118:7239-7240.

共引文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部