多器官功能障碍综合征诊断标准(草案)对患者病情严重度的评估

The stardard of multiple organ disfunction sydrome(draft) evaluating the severity of patients with mods

目的 多器官功能障碍综合征(MODS)诊断标准(草案)对MODS患者病情预后的评估进行评价.方法 多中心、前瞻性收集自2003～2005年的725例MODS患者的临床资料,应用方差分析、受试者工作特征(ROC)曲线等对患者预后进行统计分析,并与序贯性器官衰竭评价系统(SOFA评分)和Marshall评分比较.结果 725例MODS患者总死亡率为58.2%,Marshall评分、SOFA评分、草案评分和患者结局的受试者工作特征(ROC)曲线下面积分别为0.717,0.701,0.734.结论 MODS草案评分对国内MODS患者病情预后的评估优于Marshall和SOFA评分.

Objective To evaluate the severity and outcome of patients with mods via our stardard of multiple organ disfunction sydrome.Methods 725 patients with MODS from 2003 to 2005 was studied prospectively. With Reciever Operating Characteristic(ROC) Curve our standard was performed to identify risk facters compared with the standards of sofa and marshall.Results The overall motality of 58.2% is still high.The area of ROC-curves of our standard , the standards of sofa and Marshall are 0.734 0.701 and 0.717 respectively, the cutoff piont are 5,5 and 7 respectively,The sensitivity are 75%,73% and 71% respectively,and the speciality are74%,71% and 68% respectively.Conclusion Our standard is superior to the standards of sofa and marshall.