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乳腺癌48例新辅助化疗前后超声声像图的变化

Ultrasound changes of 48 patients with advanced local breast cancer before and after neoadjuvant chemotherapy
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摘要 目的探讨超声对乳腺癌新辅助化疗疗效评价的意义。方法48例进行新辅助化疗的乳腺癌患者,均于化疗前、化疗后对乳腺癌原发灶进行声像图的观察及分析。结果48例患者新辅助化疗后超声检查显示,化疗前后原发灶明显缩小甚至消失,原发灶内血流丰富程度降低或消失;最高流速(Vmax),和阻力指数(RI)降低(P<0.01,P<0.01);相应病例腋窝淋巴结转移灶也呈现上述表现。结论利用对乳腺病灶化疗前后的超声检查,可为新辅助化疗提供有效、安全的疗效观察手段。 Objective To investigate the value of ultrasound changes of breast cancer in evaluation of therapeutic effect of neoadjuvant chemo-therapy in locally advanced breast cancer.Methods The primarly lesion and axillary nodes of48 patients with breast cancer were examined by col-or doppler ultrasound before and after neoadjuvant chemotherapy.Results After neoadjuvant chemotherapy, the primarly lesion and its blood vol-ume significantly decreased and even disappeared, Vmax and RI also reduced. The same changes were observed in the metastatic lymph nodes.Conclusion Ultrasonography is an effective non -invasive way for the evaluation of results of neoadjuvant chemotherapy.
作者 赵红梅 刘真真 张恒伟 王雁 崔树德
机构地区 河南省肿瘤医院超声科 河南省肿瘤医院乳腺科
出处 《临床和实验医学杂志》 2006年第9期1300-1301,共2页 Journal of Clinical and Experimental Medicine
关键词 超声检查 乳腺癌 新辅助化疗 Ultrasound Bbreast cancer Neoadjuvant chemotherapy
分类号 R737.9 [医药卫生—肿瘤]
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参考文献4

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二级参考文献12

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临床和实验医学杂志
2006年 第9期

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