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尿胰蛋白酶原-2在筛查急性胰腺炎临床应用中的评价 被引量:6

Evaluation of clinical application of urinary trypsinogen-2 assay as a screening test for acute pancreatitis
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摘要 目的评价尿胰蛋白酶原-2试纸条在筛查急性胰腺炎中的临床价值。方法收集50例急腹症患者的血清和尿液,按最终诊断分为急性胰腺炎组(22例)和非急性胰腺炎组(28例),分别检测尿胰蛋白酶原-2,血淀粉酶和尿淀粉酶,并将结果进行比较。结果尿胰蛋白酶原-2诊断急性胰腺炎的敏感性、特异性分别为96%、86%;血淀粉酶为73%、82%;尿淀粉酶为82%、86%。结论尿胰蛋白酶原-2的敏感性和阴性预期值均高于血、尿淀粉酶,可以作为急性胰腺炎诊断的筛选指标。 Objective To evaluate the clinical value of the dipstick test for urinary trypsinogen-2 in screening of acute pancreatitis.Methods Serum and urine samples from 50 patients with acute abdomen were collected and divided into two groups according to the standardized criteria:acute pancteatitis group(22 patients) and non-acute pancreatitis group(28 patients).Urine trypsinogen-2,serum amylase, urine amylase were respectively detected and compared.Results The sensitivity,specificity of urinary trypsinogen-2 dipstick test were 96%,86%,and those of serum amylase were73%,82%,those of urine amylase were 82%,86%.Conclusion Because the sensitivity and negative predictive values of urinary trypsinogen-2 are better than those of serum amylase and urine amylase,it can be used for screening test in the diagnosis of acute pancreatitis.
作者 李新丽 程江
出处 《检验医学与临床》 CAS 2006年第2期55-56,共2页 Laboratory Medicine and Clinic
关键词 尿胰蛋白酶原-2 淀粉酶 急性胰腺炎 Urinary trypsinogen-2 Amylase Acute pancreatitis
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参考文献9

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二级参考文献3

  • 1Yasuyuki Nakae,Satoru Naruse,Motoji Kitagawa,Hiroshi Ishiguro,Masanori Kato,Shinobu Hayakawa,Takaharu Kondo,Tetsuo Hayakawa. Molecular forms of serum pancreatic stone protein in acute pancreatitis[J] 1999,International Journal of Pancreatology(1):17~21
  • 2Scott Tenner,Carlos Fernandez-del Castillo,Andrew Warshaw,William Steinberg,John Hermon-Taylor,Jorge E. Valenzuela,Mohammed Hariri,Michael Hughes,Peter A. Banks. Urinary trypsinogen activation peptide (TAP) predicts severity in patients with acute pancreatitis[J] 1997,International Journal of Pancreatology(2):105~110
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