低机械指数谐波超声造影评估肝细胞癌介入治疗效果

Significance of contrast-enhanced harmonic sonography with low mechanical index to evaluate the therapeutic responses of interventional treatment for hepatocellular carcinoma

目的探讨低机械指数谐波超声造影在肝细胞癌(HCC)介入治疗中对疗效的评估价值。方法对82例介入治疗的HCC患者分别于治疗前后进行低机械指数超声谐波造影、常规二维灰阶超声、彩色多普勒血流成像(CDFI)和增强CT和(或)MRI检查,记录病灶数目、大小,观察病灶内血供。结果82例患者介入治疗前二维超声及CDFI共检出病灶119个,超声造影共检出病灶142个;治疗前后超声造影显示病灶范围均较二维超声所示增大;病灶内血流信号检测以超声造影最准确。结论超声造影能较好地评估HCC介入治疗的疗效。

s] Objective To investigate the value of contrast-enhanced harmonic sonography with low mechanical index to evaluate the therapeutic responses of interventional treatment for hepatocellular carcinoma (HCC). Methods Eighty-two patients with HCC underwent contrast-enhanced harmonic sonography with low mechanical index, routine gray scale ultrasonography, color Doppler flow imaging (CDFI), and contrast-enhanced CT/MRI before and after interventional treatment. The number and dimension of the lesions were recorded. Blood signs in the tumors were observed. Results One hundred and nineteen lesions were visualized on routine gray scale ultrasonography and CDFI. Totally 142 lesions were detected by contrast-enhanced sonography in 82 patients. The diameter of the lesions shown by contrast-enhanced sonography was larger than that by routine gray scale ultrasonography. The results of detecting blood flow in the tuomor on contrast-enhanced sonography were consistant with contrast-enhanced CT/MRI of 90.8%(129/142) lesions. Conclusions Contrast-enhanced sonography is a valuable modality for assessing the therapeutic effects of interventional treatment for hepatocellular carcinoma.