急性乙醇中毒者血清尿酸含量及其与血清乙醇含量的相关性分析

Analysis of the Uric Acid and its Correlation with the Ethyl Alcohol in Patients with Acute Alcoholism

[目的]探讨急性乙醇中毒对血清尿酸含量的影响,分析血清乙醇含量与尿酸含量的相关性。[方法]对2004年6月至2005年9月到厦门市仙岳医院接受醒酒治疗的434例急性乙醇中毒者进行血清尿酸检测,并与356名健康人进行比较。[结果]血清尿酸含量急性乙醇中毒者为(426.62±103.42)mmol/L,正常对照组为(349.86±62.64)mmol/L(P<0.01);急性乙醇中毒者血清尿酸含量与乙醇浓度间无相关关系(r=1.98×10-8,P>0.05)。[结论]急性乙醇中毒可引起血清尿酸含量明显增高。

[Objective]To investigate the effects of the acute alcoholism on the uric acid in serum and analyze the correlation between the uric acid and the ethyl alcohol.[Methods]The uric acid in serum in 434 cases of patients with acute alcoholism was determined in Xianyue Hospital of Xiamen from June 2004 to september 2005,and was compared with that among 356 persons of the control group.[Results]The uric acid in serum among 434 cases of patients with acute alcoholism was(426.62±103.42)mmol/L,and that among the control group was(349.86±62.64)mmol/L(P<0.01).The uric acid in serum was zero correlation with ethyl alcohol in patients with acute alcoholism.[Conclusion]Acute alcoholism may cause the higher uric acid in serum.