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人类血小板抗原HPA-15(Gov)在中国汉族人群中的分布及其在血小板输注中的意义

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摘要   血小板同种抗原包括与其它细胞和组织共有的抗原,以及血小板本身特有的抗原,被称为血小板同种特异性抗原(human platelet alloantigen,HPA)[1].目前已有22个HPA抗原被正式命名,相应基因遗传多态性的分子基础也被阐明[2].由于HPA抗原介导同种抗体的产生,能够引发同种免疫性血小板减少,所以对HPA进行准确的分型,对于避免PTP及PTR的发生[3],提高输血的安全性及有效性具有重要意义.……
机构地区 上海市血液中心
出处 《中国输血杂志》 CAS CSCD 2006年第z1期97-99,共3页 Chinese Journal of Blood Transfusion
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参考文献8

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二级参考文献12

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