关于中药复方研究的几点思考

Development of the Research Methods Based on the Characteritics of the Traditional Chinese Prescription

目的:综述近年来中药复方化学和药理研究方法的进展。方法:查阅近年来关于中药化学和中药药理研究方法的文献,进行归纳整理并分类汇总。结果:回顾文献并结合作者实验室最近研究工作,提出了对中药复方研究方法的一些思考:加强中药药理指导下化学研究;建立中药复方化学分析和代谢物组学研究方法;建立药效物质评价指标体系和加强有效成分研究等。结论:多学科协作、新方法的涌现会对复方研究带来发展。

Objective:To review the development of the research methods of the chemistry and pharmacology of the traditional Chinese medicine(TCM)in recent years,and present some thoughts.Methods:Papers reported in journals were consulted and classified,according to the research methods of the TCM.Results:Combining the summary and the latest studies of our laboratory,some thoughts about TCM were offered,such as strengthening the research of chemistry;establishing the study methods of the metabonomics;evaluating the pharmacodynamic material;studying the effective compounds,and so on.Conclusions:The deeper cooperation among the correlative subjects and flood of new thoughts would accelerate the study of TCM.