产舒颗粒的药材鉴定和含量测定

Identification and content determination of Chanshu granule

目的建立产舒颗粒的质量控制方法。方法采用TLC法鉴别人参、当归和酸枣仁;采用RP-HPLC法测定产舒颗粒中的人参皂苷Rb1。结果TLC可鉴别人参、当归和酸枣仁的特征斑点。HPLC测定中,人参皂苷Rb10.776~7.760μg.ml-1线性关系良好(r=0.9999),平均回收率99.69%,RSD=2.04%。结论所建方法简便、准确,可有效控制产舒颗粒的质量。

OBJECTIVE To establish the quality control method for Chanshu granule.METHODSRadix Ginseng,semen Ziziphi spinosae and radix Angelicae sinensis were identified by TLC,and the content of ginsenoside Rb1 of Chanshu granule was determined by RP-HPLC.RESULTSThe special spots of radix Ginseng,semen Ziziphi spinosae and radix Angelicae sinensis could be identified by TLC.For HPLC detecmination,the linear correlation was available between 0.776 and 7.760 g·ml-1of ginsenoside Rb1,and the correlation coefficient was ...