感冒颗粒中药材的鉴定及绿原酸、橙皮苷的测定

Identification of crude drug and determination of chlorogenic acid,hesperidin for Cold pellets

目的制定感冒颗粒的质量标准。方法用TLC鉴别制剂中鱼腥草、薄荷、甘草、陈皮;采用HPLC法测定绿原酸、橙皮苷的含量。结果TLC色谱中均能明显地检出鱼腥草、薄荷、甘草、陈皮;HPLC法测得绿原酸含量为0.63%,平均回收率为99.54%,RSD=0.87%(n=9);橙皮苷含量为0.58%,平均回收率为99.75%,RSD=1.13%(n=9)。结论定性、定量方法简便、准确、专属性强,能有效地控制感冒颗粒的质量。

OBJECTIVE To establish a method for quality control of cold pellets.METHODS Fish rank grass,Peppermint,Licorice,Dried orange peel were identified by TLC.The content of chlorogenic acid,hesperidin was determined by HPLC.RESULTS Fish rank grass,Peppermint,Licorice,Dried orange peel could be identified by TLC.The content of chlorogenic acid determined by HPLC was 0.63% and the RSD was 0.87%(n=9).The content of hesperidin determined by HPLC was 0.58% and RSD was 1.13%(n=9).CONCLUTION This method is simple,accur...