老年人轻度帕金森病样体征与轻度认知功能损害的关系

Study on the association between mild parkinsonian signs in elderly persons and mild cognitive impairment

目的:比较轻度帕金森病样体征(mild parkinsonian signs,MPS)和无MPS老人的轻度认知功能损害(mildcognitive impairment,MCI)患病情况,探讨MPS与MCI间的关系。方法:以506名大于70岁老年人为研究对象,使用国际通用帕金森病统一评分量表(The unified Parkinson's disease rating scale,UPDRS)第Ⅲ部分缩写版本评定MPS。将研究对象分为MPS组和无MPS组,分析MPS患病的危险因素及MCI患病情况。结果:MPS组较无MPS组的年龄大,患糖尿病及MCI比例高。结论:MPS与MCI的关系密切,不同类型的MPS对MCI的发病影响不同。

Objective:To observe presence of mild parkinsonian signs(MPS)in elderly and explore the association between MPS and mild cognitive impairment(MCI)in the elderly persons.Methods:506 persons aged over 70 years were assessed MPS and MCI.MPS were rated with an abbreviated version of the motor portion of the Unified Parkinson s Disease Rating Scale(UPDRS).The risk factors for presence of MPS were studied.Comparisons of the prevalence of MCI were made between the groups of elderly with MPS and without MPS.Results...