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鉴别额叶癫痫及颞叶癫痫的临床症状学提示 被引量:11

Predictive Clinical Semiological Factors for the Differential Diagnosis of Frontal Lobe Epilepsy and Temporal Lobe Epilepsy
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摘要 目的:比较额叶癫痫(FLE)及颞叶癫痫(TLE)的临床症状学区别。方法:纳入2005年10月至2007年3月我院癫痫中心门诊临床诊断为额叶癫痫患者190名,颞叶癫痫患者257名。纳入病例满足发作间期脑电图至少一次具有局限于额叶或颞叶的放电或发作期脑电图明确提示额或颞叶起源;排除所有发作间期脑电图正常、存在多灶或定位不清的脑电异常及影像学检查具有额或颞叶以外的局灶损害者。由两位不知道患者脑电图和影像学结果的临床医生单独分析患者发作情况(先兆、复杂部分发作(CPS)、继发全面强直阵挛发作(SGTC))。用χ2检验统计数据。结果:提示颞叶癫痫最有意义的先兆是经验现象和胃气上升感(P<0.01)。情感表现在TLE中更常见(P<0.05)。口咽自动症与手部自动症是颞叶癫痫患者的典型CPS表现(P<0.01)。而躯体自动症,偏转性强直-肢体与头眼及SGTC、姿势性强直,局部阵挛发作,发作时伴随出声、植物神经症状是额叶癫痫患者的典型CPS表现(P<0.01)。发笑、震颤症状在二类中均可出现,以额叶居多(P<0.05)。言语终止,自言自语,单纯凝视发作对于二者的鉴别意义不大。额叶癫痫组具有两种以上CPS发作的病例更多(P<0.01)。结论:额叶癫痫与颞叶癫痫的症状学特征是不同的,对于临床诊断有重要价值。 Objective:To describe predictive clinical semiological characters for the differentiation between frontal lobe epilepsy(FLE)and temporal lobe epilepsy(TLE).Methods:Two independent,blinded investigators analyzed all seizures(aura,complex partial seizure,SGTC)from 190 patients with FLE and 257 patients with TLE diagnosed between Oct.2005 and Mar.2007.We included patients with regional frontal or temporal EEG and excluded patients without EEG abnormality and patients with nonlocalizing EEG abnormalities and fo...
出处 《脑与神经疾病杂志》 2008年第3期202-205,共4页 Journal of Brain and Nervous Diseases
关键词 额叶癫痫 颞叶癫痫 发作症状学 先兆 Frontal lobe epilepsy Temporal lobe epilepsy Seizure semiology Aura
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参考文献17

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共引文献31

同被引文献67

  • 1张华,大槻泰介.癫痫过度运动发作的症状分析[J].立体定向和功能性神经外科杂志,2003,16(2):75-77. 被引量:4
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