医用钛表面生物活性化研究

Progress in the surface bioactivation for titanium in medicine

钛及钛合金具有优良的生物相容性和机械性能,已应用于临床,尤其是用作骨替换与修复材料。但是,钛属于生物惰性材料.不能与骨组织形成化学键合或称骨键合。通过表面改性可使其在生理环境具有诱导羟基磷灰石在表面自发生长的能力,即生物活性化。这是当今生物医用材料研究的热点领域之一。本文评述了钛表面生物活化的研究现状,简要总结了本课题组在这方面的研究工作。

Titanium and its alloys as bone-substitutes have been used clinically for bone-substitute biomaterials due to their excellent biocompatibility.mechanical properties. However, titanium cannot bone-bond with bone tissue and was thought to be bioinnert, By the surface modification, titanium could induce the spontaneous formation of hydroxyapatite on the surfaces in biological environment. Recently, the surface bioactivation for titanium was one of hot points in biomedical materials. The present paper reviews the current status in this field and summarized the work of our group.