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表皮生长因子受体靶向治疗在非小细胞肺癌的进展

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摘要   肺癌是恶性肿瘤中高发病率、主要致死性疾病.NSCLC占肺癌总数80%,大部分患者初诊即为晚期,许多早期患者手术根治后仍出现复发、转移,临床缓解和提高患者生存质量仍是主要治疗目标.   ……
作者 陈龙 李惠梅
出处 《中国现代应用药学》 CAS CSCD 北大核心 2005年第z2期714-716,共3页 Chinese Journal of Modern Applied Pharmacy
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参考文献18

  • 1[1]Ciardiello F, Giampaolo T. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin Cancer Res, 2001;7(10):2958-2970.
  • 2[2]Tien H, Anne MT, Joan HS. Novel therapies for lung cancer. Surg Oncol,2002;11 (4) 229-241.
  • 3[3]Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomizedphase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. Clin Oncol, 2003;21(12):2237-2246.
  • 4[4]Kris MG, Natale BR, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer a randomized trial. JAMA, 2003;290(16):2149 2158.
  • 5[5]Copin M, Kommareddy A, Behnken D, et al. Gefitinib in elderly patients with non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol, 2003;(22):758-761.
  • 6[6]Gridelli C, Maione P, Castaldo V,et al. Gefitinib in elderly and unfit patients affected by advanced non-small cell lung cancer. Br J Cancer, 2003;(89):1827 1829.
  • 7[7]Cappuzzo F, Bartolini S, Ceresoli GL, et al. Efficacy and tolerability of gefitinib in pretreated elderly patients with advanced non-small-cell lung cancer (NSCLC). Br J Cancer, 2004;(90):82 86.
  • 8[8]Giaccone G, Johnson DH, Manegold C, et al. A phase III clinical trial of ZD1839 (Iressa) in combination with gemcitabine and cisplatin in chemotherapy-naive patients with advanced non-smallcell lung cancer (INTACT 1) . Ann Oncol,2002;(13):2-6.
  • 9[9]Johnson DH, Herbst R, Giaccone G, et al. ZD1839 (Iressa) in combination with paclitaxel, ZD1839 (Iressa) in combination with paclitaxel & carboplatin in chemotherapy-naive patients with advanced non-small cell lung cancer (NSCLC): results from a phaseIII clinical trial (INTACT 2) . Ann Oncol, 2002;(13):127-132.
  • 10[10]Fandi A, Gatzemeier U, Smith R, Averbuch S, Manegold C. Final data from a pilot trial of gefitinib (ZD1839) in combination with docetaxel in patients with advanced or metastatic non-small-cell lung cancer (NSCLC): safety and pharmacokinetics. Proc Am Soc Clin Oncol, 2003;(22):655-663.

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