冠状动脉病变与脂蛋白(a)相关性分析

Correlation analysis of the severity of coronary artery lesion and lipoprotein(a)

目的:探讨冠心病患者冠状动脉病变范围及狭窄程度与脂蛋白(a)的关系。方法:387例选择性冠状动脉造影,252例冠状动脉造影证实冠心病患者按病变范围、狭窄程度分组,术前行脂蛋白(a)[Lp(a)]检查,对比分析冠状动脉病变范围及狭窄程度与Lp(a)的关系。结果:1Lp(a)各病变范围组与正常对照组均有差异(P<0.01),各病变范围组间亦有差异(P<0.05或P<0.01);2Lp(a)各病变组与正常对照组均有差异(P<0.01),Lp(a)完全闭塞组与轻、中度狭窄组均有差异(P<0.05)。结论:冠心病患者随着病变范围的增加,Lp(a)明显升高,随着狭窄程度的加重,Lp(a)亦升高,但变化不明显。

Objective:To investigate the relationship between the degree of coronary artery stenosis and lipoprotein(a).Method:We studied 387 patients who underwent selective coronary arteriography(CAG).252 patients,who were diagnosed as coronary heart disease(CAD)by CAG,were devided into different groups according to the extent of lenghth and stenosis of the artery affection,and examine the level of lipoprotein A[Lp(a)]before CAG.We analysised the correlation between the scope of coronary disease and the level of LP A...