银杏达莫注射液对原发性肾病综合征血脂及血流变学的影响

The Influence of Injection Gingko Damo to Blood-Fat and Rheological in Primarily Hydropigenous Nephritis

目的研究银杏达莫注射液对肾病综合症血脂及血流变的影响。方法选取84例肾病综合症患者,随机分为两组,均正规激素治疗,治疗组同时加用银杏达莫注射液注射21d,用药时期均停用潘生丁、肝素等抗凝及降脂药物。观察两组前后血清白蛋白、24h尿蛋白定量、血脂、血流变、凝血指标的变化。结果治疗组血浆白蛋白、24h尿蛋白定量、血液黏度、血小板凝聚率、血清总胆固醇、甘油三脂、血凝指标与治疗前比较有显著性差异(P<0.01、P<0.05);治疗后,上述指标与对照组比较亦有显著性差异(P<0.01、P<0.05)。结论银杏达莫注射液可治疗原发性肾病综合症,可降低蛋白尿、血脂、血黏度,具有明显改善患者高凝状态的特效作用。

Objective To study the influence of injection Gingko damo to blood-fat and rheology of patients with Primarily Hydropigenous nephritis.Methods Eighty-four patients with Primarily Hydropigenous nephritis were randomly seleced and divided into two groups.Two groups were both treated with hormone regularly.GroupⅠ was treated with injection Gingko damo for twenty-two days additionally.During the period of treatment we stopped using anticoagulation agents,such as Persantine and Heparin,and lipid-lowing agents.To...